BASF Licenses CRISPR-Cpf1 Genome Editing Technology From The Broad Institute of MIT and Harvard

With protein assays, scientists can quantify proteins in plant extracts. Experiments in the protein analytics lab help with the development and characterization of traits. BASF Plant Science develops traits that make plants more resistant to fungal pathogens, tolerant to herbicides or produce higher yields.

Research Triangle Park, NC (October 24, 2018) – BASF has attained a global, non-exclusive licensing agreement with the Broad Institute of MIT and Harvard for the use of CRISPR-Cpf1 genome editing technology to improve products in agricultural and industrial microbiology applications.

CRISPR-Cpf1 has demonstrated distinct advantages for certain applications over CRISPR-Cas9, which BASF has previously licensed from the Broad Institute. By adding CRISPR-Cpf1 to its portfolio, BASF has the flexibility to choose the right tool for specific applications. Access to both technologies will also help to accelerate the development of new agricultural and industrial microbiology products.

“Genome editing tools represent the next step in molecular biology innovation,” said Peter Eckes, President of BASF Bioscience Research. “The addition of CRISPR-Cpf1 greatly expands our technological capabilities in modern agriculture and industrial solutions and we are eager to see how these technologies will improve multiple products in these areas.”

“This technology represents a transformative application of genome editing for the research community,” said Issi Rozen, Chief Business Officer of the Broad Institute. “CRISPR-Cpf1 can directly benefit advanced research across many industries including human health and agriculture. We are proud to partner with stakeholders throughout the biomedical and agriculture community to help deliver responsible solutions for our planet.”


BASF Corporation, headquartered in Florham Park, New Jersey, is the North American affiliate of BASF SE, Ludwigshafen, Germany. BASF has more than 18,200 employees in North America, and had sales of $17.9 billion in 2017. For more information about BASF’s North American operations, visit www.basf.com.

At BASF, we create chemistry for a sustainable future. We combine economic success with environmental protection and social responsibility. The more than 115,000 employees in the BASF Group work on contributing to the success of our customers in nearly all sectors and almost every country in the world. Our portfolio is organized into five segments: Chemicals, Performance Products, Functional Materials & Solutions, Agricultural Solutions and Oil & Gas. BASF generated sales of €64.5 billion in 2017. BASF shares are traded on the stock exchanges in Frankfurt (BAS), London (BFA) and Zurich (BAS). Further information at www.basf.com.

BASF technicians in a white biotechnology research lab in Germany are working with microorganisms to produce enzymes.